Steam reformers are used in ammonia, methanol and hydrogen plants and are one of the most critical items of equipment in terms of the potential impact on safety and production in case of failure. Reformer tubes operate within the creep range, and thus their useful life is finite and highly dependent on the operating conditions. Knowledge and the rigorous application of sound practices are required to ensure the proper management of the tubes from design to fabrication, installation, inspection, and ending with safe retirement after the conclusion of their lifecycle.